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Dokumenttyp:
journal article 
Autor(en):
Yan, YK; Melchart, M; Habtemariam, A; Sadler, PJ 
Titel:
Organometallic chemistry, biology and medicine: ruthenium arene anticancer complexes. 
Abstract:
Our work has shown that certain ruthenium(II) arene complexes exhibit promising anticancer activity in vitro and in vivo. The complexes are stable and water-soluble, and their frameworks provide considerable scope for optimising the design, both in terms of their biological activity and for minimising side-effects by variations in the arene and the other coordinated ligands. Initial studies on amino acids and nucleotides suggest that kinetic and thermodynamic control over a wide spectrum of reac...    »
 
Zeitschriftentitel:
Chem Commun (Camb) 
Jahr:
2005 
Heft / Issue:
38 
Seitenangaben Beitrag:
4764-76 
Sprache:
eng 
Print-ISSN:
1359-7345 
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik