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Document type:
journal article 
Author(s):
Hafsi, N; Voland, P; Schwendy, S; Rad, R; Reindl, W; Gerhard, M; Prinz, C 
Title:
Human dendritic cells respond to Helicobacter pylori, promoting NK cell and Th1-effector responses in vitro. 
Abstract:
Helicobacter pylori infection leads to chronic gastric inflammation. The current study determined the response of human APCs, NK cells, and T cells toward the bacteria in vitro. Human monocyte-derived dendritic cells (DC) were incubated with bacteria for 48 h. Intact H. pylori at a multitude of infection 5 stimulated the expression of MHC class II (4- to 7-fold), CD80, and CD86 B7 molecules (10- to 12-fold) and the CD83 costimulatory molecule (>30-fold) as well as IL-12 secretion (>50-fold) in D...    »
 
Journal title abbreviation:
J Immunol 
Year:
2004 
Journal volume:
173 
Journal issue:
Pages contribution:
1249-57 
Language:
eng 
Print-ISSN:
0022-1767 
TUM Institution:
II. Medizinische Klinik und Poliklinik