Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Schreiner, B; Greten, FR; Baur, DM; Fingerle, AA; Zechner, U; Böhm, C; Schmid, M; Hameister, H; Schmid, RM 
Titel:
Murine pancreatic tumor cell line TD2 bears the characteristic pattern of genetic changes with two independently amplified gene loci. 
Abstract:
TGFalpha/p53(+/-) transgenic mice represent a genetically engineered mouse model for pancreatic adenocarcinoma. The tumors develop a characteristic pattern of secondary genetic changes. From one of these tumors, the permanent cell line TD2 was established. Here, we describe in detail the genetic changes by molecular-cytogenetic techniques. The original tumor-specific CGH profile has been retained unchanged. The most characteristic aberration pattern bears chromosome 11. Egfr, localized on proxim...    »
 
Zeitschriftentitel:
Oncogene 
Jahr:
2003 
Band / Volume:
22 
Heft / Issue:
43 
Seitenangaben Beitrag:
6802-9 
Sprache:
eng 
Print-ISSN:
0950-9232 
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik