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Document type:
journal article 
Author(s):
Nührenberg, TG; Voisard, R; Fahlisch, F; Rudelius, M; Braun, J; Gschwend, J; Kountides, M; Herter, T; Baur, R; Hombach, V; Baeuerle, PA; Zohlnhöfer, D 
Title:
Rapamycin attenuates vascular wall inflammation and progenitor cell promoters after angioplasty. 
Abstract:
Rapamycin combines antiproliferative and antiinflammatory properties and reduces neointima formation after angioplasty in patients. Its effect on transcriptional programs governing neointima formation has not yet been investigated. Here, we systematically analyzed the effect of rapamycin on gene expression during neointima formation in a human organ culture model. After angioplasty, renal artery segments were cultured for 21 or 56 days in absence or presence of 100 ng/ml rapamycin. Gene expressi...    »
 
Journal title abbreviation:
FASEB J 
Year:
2005 
Journal volume:
19 
Journal issue:
Pages contribution:
246-8 
Language:
eng 
Print-ISSN:
0892-6638 
TUM Institution:
I. Medizinische Klinik und Poliklinik