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Document type:
journal article 
Author(s):
Schreiber, C; Heimisch, W; Schad, H; Brkic, A; Badiu, C; Lange, R; Bauernschmitt, R 
Title:
C1-INH and its effect on infarct size and ventricular function in an acute pig model of infarction, cardiopulmonary bypass, and reperfusion. 
Abstract:
BACKGROUND: Recent studies suggest that complement inhibition reduces reperfusion injury. A clinical setting with local application of a C1 esterase inhibitor (C1-INH) has been modeled in an animal study in order to further investigate these findings. METHODS: In 21 pigs, the left anterior descending coronary artery (LAD) was occluded distally to the first diagonal branch for 2 hours (h), including 1 h of cardioplegic arrest during CPB. After release of the coronary snare, C1-INH or NaCl (contro...    »
 
Journal title abbreviation:
Thorac Cardiovasc Surg 
Year:
2006 
Journal volume:
54 
Journal issue:
Pages contribution:
227-32 
Language:
eng 
Print-ISSN:
0171-6425 
TUM Institution:
chirurgie