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Dokumenttyp:
journal article 
Autor(en):
Ramus, SJ; Kartsonaki, C; Gayther, SA; Pharoah, PD; Sinilnikova, OM; Beesley, J; Chen, X; McGuffog, L; Healey, S; Couch, FJ; Wang, X; Fredericksen, Z; Peterlongo, P; Manoukian, S; Peissel, B; Zaffaroni, D; Roversi, G; Barile, M; Viel, A; Allavena, A; Ottini, L; Papi, L; Gismondi, V; Capra, F; Radice, P; Greene, MH; Mai, PL; Andrulis, IL; Glendon, G; Ozcelik, H; OCGN; Thomassen, M; Gerdes, AM; Kruse, TA; Cruger, D; Jensen, UB; Caligo, MA; Olsson, H; Kristoffersson, U; Lindblom, A; Arver, B; Karls...    »
 
Titel:
Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers. 
Abstract:
Germline mutations in the BRCA1 and BRCA2 genes are associated with increased risks of breast and ovarian cancers. Although several common variants have been associated with breast cancer susceptibility in mutation carriers, none have been associated with ovarian cancer susceptibility. A genome-wide association study recently identified an association between the rare allele of the single-nucleotide polymorphism (SNP) rs3814113 (ie, the C allele) at 9p22.2 and decreased risk of ovarian cancer fo...    »
 
Zeitschriftentitel:
J Natl Cancer Inst 
Jahr:
2011 
Band / Volume:
103 
Heft / Issue:
Seitenangaben Beitrag:
105-16 
Sprache:
eng 
Print-ISSN:
0027-8874 
TUM Einrichtung:
Frauenklinik und Poliklinik