Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
du Bois, A; Burges, A; Meier, W; Pfisterer, J; Schmalfeldt, B; Richter, B; Jackisch, C; Staehle, A; Kimmig, R; Elser, G 
Titel:
Pegylated liposomal doxorubicin and carboplatin in advanced gynecologic tumors: a prospective phase I/II study of the Arbeitsgemeinschaft Gynaekologische Onkologie Studiengruppe Ovarialkarzinom (AGO-OVAR). 
Abstract:
BACKGROUND: Single-agent platinum and single-agent pegylated liposomal doxorubicin (PLD) are both effective in the treatment of gynecologic malignancies. Based on evidence that combination platinum-containing regimens offer superior efficacy versus single-agent regimens, we conducted this study to determine the maximum tolerated dose (MTD) of PLD in combination with carboplatin. PATIENTS AND METHODS: In this phase I/II dose-finding study, six courses of PLD (20, 30, 40 or 50 mg/m2) and carboplat...    »
 
Zeitschriftentitel:
Ann Oncol 
Jahr:
2006 
Band / Volume:
17 
Heft / Issue:
Seitenangaben Beitrag:
93-6 
Sprache:
eng 
Print-ISSN:
0923-7534 
TUM Einrichtung:
Frauenklinik und Poliklinik