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Document type:
journal article 
Author(s):
Beaufort, N; Leduc, D; Rousselle, JC; Magdolen, V; Luther, T; Namane, A; Chignard, M; Pidard, D 
Title:
Proteolytic regulation of the urokinase receptor/CD87 on monocytic cells by neutrophil elastase and cathepsin G. 
Abstract:
The urokinase receptor (CD87) participates to the pericellular proteolytic potential of migrating cells and to the recruitment of leukocytes during inflammation. It consists of three structurally homologous domains, with the C-terminal domain D3 attached to cell membranes through a GPI anchor. CD87 is susceptible to an endoproteolytic processing removing the N-terminal domain D1 and generating truncated D2D3 membrane species, thus modulating CD87-associated functions. Full-length or truncated CD...    »
 
Journal title abbreviation:
J Immunol 
Year:
2004 
Journal volume:
172 
Journal issue:
Pages contribution:
540-9 
Language:
eng 
Print-ISSN:
0022-1767 
TUM Institution:
Frauenklinik und Poliklinik