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Dokumenttyp:
journal article 
Autor(en):
Hantke, B; Harbeck, N; Schmalfeldt, B; Claes, I; Hiller, O; Luther, MO; Welk, A; Kuhn, W; Schmitt, M; Tschesche, H; Muehlenweg, B 
Titel:
Clinical relevance of matrix metalloproteinase-13 determined with a new highly specific and sensitive ELISA in ascitic fluid of advanced ovarian carcinoma patients. 
Abstract:
Matrix metalloproteinases (MMPs) are involved in many physiological and pathophysiological processes, including tumor cell invasion and metastasis. For one member of this family, MMP-13 (collagenase-3), a new, highly specific ELISA with a sensitivity of 0.5 ng MMP-13/ml was established. The protein levels of MMP-13 in ascitic fluids of 30 patients with advanced ovarian cancer FIGO stage III (n = 19) and IV (n = 11) were measured with this ELISA. Using a cut-off value of 0.5 ng MMP-13/mg total pr...    »
 
Zeitschriftentitel:
Biol Chem 
Jahr:
2003 
Band / Volume:
384 
Heft / Issue:
Seitenangaben Beitrag:
1247-51 
Sprache:
eng 
Print-ISSN:
1431-6730 
TUM Einrichtung:
Frauenklinik und Poliklinik