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Document type:
journal article 
Author(s):
Look, M; van Putten, W; Duffy, M; Harbeck, N; Christensen, IJ; Thomssen, C; Kates, R; Spyratos, F; Fernö, M; Eppenberger-Castori, S; Fred Sweep, CG; Ulm, K; Peyrat, JP; Martin, PM; Magdelenat, H; Brünner, N; Duggan, C; Lisboa, BW; Bendahl, PO; Quillien, V; Daver, A; Ricolleau, G; Meijer-van Gelder, M; Manders, P; Edward Fiets, W; Blankenstein, M; Broët, P; Romain, S; Daxenbichler, G; Windbichler, G; Cufer, T; Borstnar, S; Kueng, W; Beex, L; Klijn, J; O'Higgins, N; Eppenberger, U; Jänicke, F; Sch...    »
 
Title:
Pooled analysis of prognostic impact of uPA and PAI-1 in breast cancer patients. 
Abstract:
In this report we present an extension of the pooled analysis of the prognostic impact of urokinase-type plasminogen activator (uPA) and its inhibitor PAI-I in breast cancer patients. We analyzed a different endpoint, metastasis-free survival (MFS). We checked the consistency of the estimates for uPA and PAI-1 for relapse-free survival (RFS) and MFS exploring possible sources of heterogeneity. Nodal status, the most important prognostic factor for breast cancer, introduced heterogeneity in the u...    »
 
Journal title abbreviation:
Thromb Haemost 
Year:
2003 
Journal volume:
90 
Journal issue:
Pages contribution:
538-48 
Language:
eng 
Print-ISSN:
0340-6245 
TUM Institution:
Frauenklinik und Poliklinik; r Medizinische Statistik und Epidemiologie