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Dokumenttyp:
journal article 
Autor(en):
Traidl-Hoffmann, C; Münster, I; Ring, J; Behrendt, H 
Titel:
Impact of desloratadine and loratadine on the crosstalk between human keratinocytes and leukocytes: Implications for anti-inflammatory activity of antihistamines. 
Abstract:
BACKGROUND: Desloratadine is an H1-histamine antagonist which possesses additional anti-inflammatory properties through inhibition of leukocyte activation and reduction of ICAM-1 expression on mucosal epithelial cells. So far no studies have addressed the potential anti-inflammatory activities of desloratadine and loratadine on skin keratinocytes. OBJECTIVE: In this study the capacity of desloratadine and loratadine to counteract human keratinocyte activation by interferon-gamma (IFN-gamma) was...    »
 
Zeitschriftentitel:
Int Arch Allergy Immunol 
Jahr:
2006 
Band / Volume:
140 
Heft / Issue:
Seitenangaben Beitrag:
315-20 
Sprache:
eng 
Print-ISSN:
1018-2438 
TUM Einrichtung:
r Dermatologie und Allergologie