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Dokumenttyp:
journal article 
Autor(en):
Köllisch, G; Kalali, BN; Voelcker, V; Wallich, R; Behrendt, H; Ring, J; Bauer, S; Jakob, T; Mempel, M; Ollert, M 
Titel:
Various members of the Toll-like receptor family contribute to the innate immune response of human epidermal keratinocytes. 
Abstract:
Toll-like receptors (TLRs) are important pattern recognition molecules that activate the nuclear factor (NF)-kappaB pathway leading to the production of antimicrobial immune mediators. As keratinocytes represent the first barrier against exogenous pathogens in human skin, we investigated their complete functional TLR1-10 expression profile. First, reverse transcription-polymerase chain reaction (PCR) analysis revealed a very similar pattern of TLR mRNA expression when comparing freshly isolated...    »
 
Zeitschriftentitel:
Immunology 
Jahr:
2005 
Band / Volume:
114 
Heft / Issue:
Seitenangaben Beitrag:
531-41 
Sprache:
eng 
Print-ISSN:
0019-2805 
TUM Einrichtung:
r Dermatologie und Allergologie