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Dokumenttyp:
journal article 
Autor(en):
Maier, S; Traeger, T; Entleutner, M; Westerholt, A; Kleist, B; Hüser, N; Holzmann, B; Stier, A; Pfeffer, K; Heidecke, CD 
Titel:
Cecal ligation and puncture versus colon ascendens stent peritonitis: two distinct animal models for polymicrobial sepsis. 
Abstract:
Colon ascendens stent peritonitis (CASP) and cecal ligation and puncture (CLP), two animal models designed to closely mimic the clinical course of intra-abdominal sepsis, were compared. In the past, immunomodulatory therapies developed in animal studies failed to be successful in humans. As a consequence, the established animal sepsis models were criticized. It has been proposed that present models had to be reevaluated, and new, clinically more relevant models should be evolved. CLP procedure w...    »
 
Zeitschriftentitel:
Shock 
Jahr:
2004 
Band / Volume:
21 
Heft / Issue:
Seitenangaben Beitrag:
505-11 
Sprache:
eng 
Print-ISSN:
1073-2322 
TUM Einrichtung:
Chirurgiesche Klinik und Poliklinik