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Dokumenttyp:
journal article 
Autor(en):
Sager, Hendrik B; Heidt, Timo; Hulsmans, Maarten; Dutta, Partha; Courties, Gabriel; Sebas, Matthew; Wojtkiewicz, Gregory R; Tricot, Benoit; Iwamoto, Yoshiko; Sun, Yuan; Weissleder, Ralph; Libby, Peter; Swirski, Filip K; Nahrendorf, Matthias 
Titel:
Targeting Interleukin-1? Reduces Leukocyte Production After Acute Myocardial Infarction. 
Abstract:
Myocardial infarction (MI) is an ischemic wound that recruits millions of leukocytes. MI-associated blood leukocytosis correlates inversely with patient survival, yet the signals driving heightened leukocyte production after MI remain incompletely understood.With the use of parabiosis surgery, this study shows that soluble danger signals, among them interleukin-1?, increase bone marrow hematopoietic stem cell proliferation after MI. Data obtained in bone marrow reconstitution experiments reveal...    »
 
Zeitschriftentitel:
Circulation 
Jahr:
2015 
Band / Volume:
132 
Heft / Issue:
20 
Seitenangaben Beitrag:
1880-90 
Sprache:
eng 
Print-ISSN:
0009-7322 
TUM Einrichtung:
Klinik für Herz- und Kreislauferkrankungen