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Dokumenttyp:
journal article 
Autor(en):
Kessler, Thorsten; Zhang, Lu; Liu, Ziyi; Yin, Xiaoke; Huang, Yaqian; Wang, Yingbao; Fu, Yi; Mayr, Manuel; Ge, Qing; Xu, Qingbo; Zhu, Yi; Wang, Xian; Schmidt, Kjestine; de Wit, Cor; Erdmann, Jeanette; Schunkert, Heribert; Aherrahrou, Zouhair; Kong, Wei 
Titel:
ADAMTS-7 inhibits re-endothelialization of injured arteries and promotes vascular remodeling through cleavage of thrombospondin-1. 
Abstract:
ADAMTS-7, a member of the disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) family, was recently identified to be significantly associated genomewide with coronary artery disease. However, the mechanisms that link ADAMTS-7 and coronary artery disease risk remain elusive. We have previously demonstrated that ADAMTS-7 promotes vascular smooth muscle cell migration and postinjury neointima formation via degradation of a matrix protein cartilage oligomeric matrix protein. Because...    »
 
Zeitschriftentitel:
Circulation 
Jahr:
2015 
Band / Volume:
131 
Heft / Issue:
13 
Seitenangaben Beitrag:
1191-201 
Sprache:
eng 
Print-ISSN:
0009-7322 
TUM Einrichtung:
Klinik für Herz- und Kreislauferkrankungen