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Document type:
journal article 
Author(s):
Wobst, Jana; Kessler, Thorsten; Dang, Tan An; Erdmann, Jeanette; Schunkert, Heribert 
Title:
Role of sGC-dependent NO signalling and myocardial infarction risk. 
Abstract:
The NO/cGMP pathway plays an important role in many physiological functions and pathophysiological conditions. In the last few years, several genetic and functional studies pointed to an underestimated role of this pathway in the development of atherosclerosis. Indeed, several genetic variants of key enzymes modulating the generation of NO and cGMP have been strongly associated with coronary artery disease and myocardial infarction risk. In this review, we aim to place the genomic findings on co...    »
 
Journal title abbreviation:
J Mol Med 
Year:
2015 
Journal volume:
93 
Journal issue:
Pages contribution:
383-94 
Language:
eng 
Print-ISSN:
0946-2716 
TUM Institution:
Klinik für Herz- und Kreislauferkrankungen