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Document type:
journal article 
Author(s):
Kriegsmann, Mark; Casadonte, Rita; Kriegsmann, Joerg; Dienemann, Hendrik; Schirmacher, Peter; Kobarg, Jan Hendrik; Schwamborn, Kristina; Stenzinger, Albrecht; Warth, Arne; Weichert, Wilko 
Title:
Reliable Entity Subtyping in Non-small Cell Lung Cancer by Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry on Formalin-fixed Paraffin-embedded Tissue Specimens. 
Abstract:
Histopathological subtyping of non-small cell lung cancer (NSCLC) into adenocarcinoma (ADC), and squamous cell carcinoma (SqCC) is of utmost relevance for treatment stratification. However, current immunohistochemistry (IHC) based typing approaches on biopsies are imperfect, therefore novel analytical methods for reliable subtyping are needed. We analyzed formalin-fixed paraffin-embedded tissue cores of NSCLC by Matrix-assisted laser desorption/ionization (MALDI) imaging on tissue microarrays to...    »
 
Journal title abbreviation:
Mol Cell Proteomics 
Year:
2016 
Journal volume:
15 
Journal issue:
10 
Pages contribution:
3081-3089 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
1535-9476 
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie