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Dokumenttyp:
journal article 
Autor(en):
Kriegsmann, Mark; Casadonte, Rita; Kriegsmann, Joerg; Dienemann, Hendrik; Schirmacher, Peter; Kobarg, Jan Hendrik; Schwamborn, Kristina; Stenzinger, Albrecht; Warth, Arne; Weichert, Wilko 
Titel:
Reliable Entity Subtyping in Non-small Cell Lung Cancer by Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry on Formalin-fixed Paraffin-embedded Tissue Specimens. 
Abstract:
Histopathological subtyping of non-small cell lung cancer (NSCLC) into adenocarcinoma (ADC), and squamous cell carcinoma (SqCC) is of utmost relevance for treatment stratification. However, current immunohistochemistry (IHC) based typing approaches on biopsies are imperfect, therefore novel analytical methods for reliable subtyping are needed. We analyzed formalin-fixed paraffin-embedded tissue cores of NSCLC by Matrix-assisted laser desorption/ionization (MALDI) imaging on tissue microarrays to...    »
 
Zeitschriftentitel:
Mol Cell Proteomics 
Jahr:
2016 
Band / Volume:
15 
Heft / Issue:
10 
Seitenangaben Beitrag:
3081-3089 
Sprache:
eng 
Print-ISSN:
1535-9476 
TUM Einrichtung:
Institut für Allgemeine Pathologie und pathologische Anatomie