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Dokumenttyp:
journal article 
Autor(en):
Pfarr, Nicole; Sinn, Hans-Peter; Klauschen, Frederick; Flechtenmacher, Christa; Bockmayr, Michael; Ridinger, Kathrin; von Winterfeld, Moritz; Warth, Arne; Lorenz, Katja; Budczies, Jan; Penzel, Roland; Lennerz, Jochen K; Endris, Volker; Weichert, Wilko; Stenzinger, Albrecht 
Titel:
Mutations in genes encoding PI3K-AKT and MAPK signaling define anogenital papillary hidradenoma. 
Abstract:
Papillary hidradenoma (a.k.a. hidradenoma papilliferum) is a benign tumor of the anogenital region that almost exclusively arises in middle-aged Caucasian women. These tumors may recur and rare cases of malignant development have been reported. The genetic basis of papillary hidradenoma is currently unknown. Hence, we employed targeted high-coverage next generation sequencing interrogating 50 cancer-related genes and conventional Sanger sequencing to investigate the mutational landscape in a coh...    »
 
Zeitschriftentitel:
Genes Chromosomes Cancer 
Jahr:
2016 
Band / Volume:
55 
Heft / Issue:
Seitenangaben Beitrag:
113-9 
Sprache:
eng 
Print-ISSN:
1045-2257 
TUM Einrichtung:
Institut für Allgemeine Pathologie und pathologische Anatomie