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Dokumenttyp:
journal article 
Autor(en):
Rödel, Claus; Graeven, Ullrich; Fietkau, Rainer; Hohenberger, Werner; Hothorn, Torsten; Arnold, Dirk; Hofheinz, Ralf-Dieter; Ghadimi, Michael; Wolff, Hendrik A; Lang-Welzenbach, Marga; Raab, Hans-Rudolf; Wittekind, Christian; Ströbel, Philipp; Staib, Ludger; Wilhelm, Martin; Grabenbauer, Gerhard G; Hoffmanns, Hans; Lindemann, Fritz; Schlenska-Lange, Anke; Folprecht, Gunnar; Sauer, Rolf; Liersch, Torsten; German Rectal Cancer Study Group; Sauer, R; Hohenberger, W; Fietkau, R; Lahmer, G; Golcher,...    »
 
Titel:
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial. 
Abstract:
Preoperative chemoradiotherapy with infusional fluorouracil, total mesorectal excision surgery, and postoperative chemotherapy with fluorouracil was established by the German CAO/ARO/AIO-94 trial as a standard combined modality treatment for locally advanced rectal cancer. Here we compare the previously established regimen with an investigational regimen in which oxaliplatin was added to both preoperative chemoradiotherapy and postoperative chemotherapy.In this multicentre, open-label, randomise...    »
 
Zeitschriftentitel:
Lancet Oncol 
Jahr:
2015 
Band / Volume:
16 
Heft / Issue:
Seitenangaben Beitrag:
979-89 
Sprache:
eng 
Print-ISSN:
1470-2045 
TUM Einrichtung:
Institut für Allgemeine Pathologie und pathologische Anatomie