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Document type:
journal article 
Author(s):
Koellisch, Ulrich; Laustsen, Christoffer; Nørlinger, Thomas S; Østergaard, Jakob Appel; Flyvbjerg, Allan; Gringeri, Concetta V; Menzel, Marion I; Schulte, Rolf F; Haase, Axel; Stødkilde-Jørgensen, Hans 
Title:
Investigation of metabolic changes in STZ-induced diabetic rats with hyperpolarized [1-13C]acetate. 
Abstract:
In the metabolism of acetate several enzymes are involved, which play an important role in free fatty acid oxidation. Fatty acid metabolism is altered in diabetes patients and therefore acetate might serve as a marker for pathological changes in the fuel selection of cells, as these changes occur in diabetes patients. Acetylcarnitine is a metabolic product of acetate, which enables its transport into the mitochondria for energy production. This study investigates whether the ratio of acetylcarni...    »
 
Journal title abbreviation:
Physiol Rep 
Year:
2015 
Journal volume:
Journal issue:
Language:
eng 
Fulltext / DOI:
TUM Institution:
Nuklearmedizinische Klinik und Poliklinik