Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Wang, Qian; Vaupel, Peter; Ziegler, Sibylle I; Shi, Kuangyu 
Titel:
Exploring the quantitative relationship between metabolism and enzymatic phenotype by physiological modeling of glucose metabolism and lactate oxidation in solid tumors. 
Abstract:
Molecular imaging using PET or hyperpolarized MRI can characterize tumor phenotypes by assessing the related metabolism of certain substrates. However, the interpretation of the substrate turnover in terms of a pathophysiological understanding is not straightforward and only semiquantitative. The metabolism of imaging probes is influenced by a number of factors, such as the microvascular structure or the expression of key enzymes. This study aims to use computational simulation to investigate th...    »
 
Zeitschriftentitel:
Phys Med Biol 
Jahr:
2015 
Band / Volume:
60 
Heft / Issue:
Seitenangaben Beitrag:
2547-71 
Sprache:
eng 
Print-ISSN:
0031-9155 
TUM Einrichtung:
Nuklearmedizinische Klinik und Poliklinik; Klinik und Poliklinik für RadioOnkologie und Strahlentherapie