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Dokumenttyp:
journal article 
Autor(en):
Goris, An; Pauwels, Ine; Gustavsen, Marte W; van Son, Brechtje; Hilven, Kelly; Bos, Steffan D; Celius, Elisabeth Gulowsen; Berg-Hansen, Pål; Aarseth, Jan; Myhr, Kjell-Morten; D'Alfonso, Sandra; Barizzone, Nadia; Leone, Maurizio A; Martinelli Boneschi, Filippo; Sorosina, Melissa; Liberatore, Giuseppe; Kockum, Ingrid; Olsson, Tomas; Hillert, Jan; Alfredsson, Lars; Bedri, Sahl Khalid; Hemmer, Bernhard; Buck, Dorothea; Berthele, Achim; Knier, Benjamin; Biberacher, Viola; van Pesch, Vincent; Sindic,...    »
 
Titel:
Genetic variants are major determinants of CSF antibody levels in multiple sclerosis. 
Abstract:
Immunological hallmarks of multiple sclerosis include the production of antibodies in the central nervous system, expressed as presence of oligoclonal bands and/or an increased immunoglobulin G index-the level of immunoglobulin G in the cerebrospinal fluid compared to serum. However, the underlying differences between oligoclonal band-positive and -negative patients with multiple sclerosis and reasons for variability in immunoglobulin G index are not known. To identify genetic factors influencin...    »
 
Zeitschriftentitel:
Brain 
Jahr:
2015 
Band / Volume:
138 
Heft / Issue:
Pt 3 
Seitenangaben Beitrag:
632-43 
Sprache:
eng 
Print-ISSN:
0006-8950 
TUM Einrichtung:
Neurologische Klinik und Poliklinik