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Dokumenttyp:
journal article 
Autor(en):
Dubey, Divyanshu; Kieseier, Bernd C; Hartung, Hans Peter; Hemmer, Bernhard; Miller-Little, William A; Stuve, Olaf 
Titel:
Clinical management of multiple sclerosis and neuromyelitis optica with therapeutic monoclonal antibodies: approved therapies and emerging candidates. 
Abstract:
Therapeutic monoclonal antibodies (mAbs) are a relatively novel class of drugs that has substantially advanced immunotherapy for patients with multiple sclerosis. The advantage of these agents is that they bind specifically and exclusively to predetermined proteins or cells. Natalizumab was the first mAb in neurology to obtain approval. It is also considered one of the most potent options for annualized relapse rate reduction among available therapeutic options. Alemtuzumab is currently also app...    »
 
Zeitschriftentitel:
Expert Rev Clin Immunol 
Jahr:
2015 
Band / Volume:
11 
Heft / Issue:
Seitenangaben Beitrag:
93-108 
Sprache:
eng 
Print-ISSN:
1744-666X 
TUM Einrichtung:
Neurologische Klinik und Poliklinik