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Dokumenttyp:
journal article 
Autor(en):
Hess, G; Keller, U; Scholz, C W; Witzens-Harig, M; Atta, J; Buske, C; Kirschey, S; Ruckes, C; Medler, C; van Oordt, C; Klapper, W; Theobald, M; Dreyling, M 
Titel:
Safety and efficacy of Temsirolimus in combination with Bendamustine and Rituximab in relapsed mantle cell and follicular lymphoma. 
Abstract:
In this phase I/II study, we explored the combination of Temsirolimus with Bendamustine and Rituximab (BeRT) in patients with r/r follicular lymphoma (FL) or mantle cell lymphoma (MCL). Patients with 1-3 prior therapies received Bendamustine (90 mg/m(2), day 1+2) and Rituximab (375 mg/m(2), day 1) with Temsirolimus in doses from 25 to 75 mg added on day 1, 8, 15 of a 28-day cycle. Fifteen (11 MCL, 4 FL) patients were included in the phase I. Median age was 73 years and median pretreatment number...    »
 
Zeitschriftentitel:
Leukemia 
Jahr:
2015 
Band / Volume:
29 
Heft / Issue:
Seitenangaben Beitrag:
1695-701 
Sprache:
eng 
Print-ISSN:
0887-6924 
TUM Einrichtung:
III. Medizinische Klinik und Poliklinik