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Dokumenttyp:
journal article 
Autor(en):
Goss, Garrett M; Chaudhari, Nirupa; Hare, Joshua M; Nwojo, Raphael; Seidler, Barbara; Saur, Dieter; Goldstein, Bradley J 
Titel:
Differentiation potential of individual olfactory c-Kit+ progenitors determined via multicolor lineage tracing. 
Abstract:
Olfactory tissue undergoes lifelong renewal, due to the presence of basal neural stem cells. Multiple categories of globose basal stem cells have been identified, expressing markers such as Lgr5, Ascl1, GBC-2, and c-Kit. The differentiation potential of individual globose cells has remained unclear. Here, we utilized Cre/loxP lineage tracing with a multicolor reporter system to define c-Kit+ cell contributions at clonal resolution. We determined that reporter expression permitted identification...    »
 
Zeitschriftentitel:
Dev Neurobiol 
Jahr:
2016 
Band / Volume:
76 
Heft / Issue:
Seitenangaben Beitrag:
241-51 
Sprache:
eng 
Print-ISSN:
1932-8451 
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik