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Dokumenttyp:
journal article 
Autor(en):
Lies, Barbara; Beck, Katharina; Keppler, Jonas; Saur, Dieter; Groneberg, Dieter; Friebe, Andreas 
Titel:
Nitrergic signalling via interstitial cells of Cajal regulates motor activity in murine colon. 
Abstract:
In the enteric nervous systems, NO is released from nitrergic neurons as a major inhibitory neurotransmitter. NO acts via NO-sensitive guanylyl cyclase (NO-GC), which is found in different gastrointestinal (GI) cell types including smooth muscle cells (SMCs) and interstitial cells of Cajal (ICC). The precise mechanism of nitrergic signalling through these two cell types to regulate colonic spontaneous contractions is not fully understood yet. In the present study we investigated the impact of en...    »
 
Zeitschriftentitel:
J Physiol 
Jahr:
2015 
Band / Volume:
593 
Heft / Issue:
20 
Seitenangaben Beitrag:
4589-601 
Sprache:
eng 
Print-ISSN:
0022-3751 
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik