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Dokumenttyp:
journal article 
Autor(en):
Fischer, Annegret; Ellinghaus, David; Nutsua, Marcel; Hofmann, Sylvia; Montgomery, Courtney G; Iannuzzi, Michael C; Rybicki, Benjamin A; Petrek, Martin; Mrazek, Frantisek; Pabst, Stefan; Grohé, Christian; Grunewald, Johan; Ronninger, Marcus; Eklund, Anders; Padyukov, Leonid; Mihailovic-Vucinic, Violeta; Jovanovic, Dragana; Sterclova, Martina; Homolka, Jiri; Nöthen, Markus M; Herms, Stefan; Gieger, Christian; Strauch, Konstantin; Winkelmann, Juliane; Boehm, Bernhard O; Brand, Stephan; Büning, Car...    »
 
Titel:
Identification of Immune-Relevant Factors Conferring Sarcoidosis Genetic Risk. 
Abstract:
Genetic variation plays a significant role in the etiology of sarcoidosis. However, only a small fraction of its heritability has been explained so far.To define further genetic risk loci for sarcoidosis, we used the Immunochip for a candidate gene association study of immune-associated loci.Altogether the study population comprised over 19,000 individuals. In a two-stage design, 1,726 German sarcoidosis cases and 5,482 control subjects were genotyped for 128,705 single-nucleotide polymorphisms...    »
 
Zeitschriftentitel:
Am J Respir Crit Care Med 
Jahr:
2015 
Band / Volume:
192 
Heft / Issue:
Seitenangaben Beitrag:
727-36 
Sprache:
eng 
Print-ISSN:
1073-449X 
TUM Einrichtung:
Institut für Humangenetik