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Dokumenttyp:
journal article 
Autor(en):
Kelwick, Richard; Wagstaff, Laura; Decock, Julie; Roghi, Christian; Cooley, Lindsay S; Robinson, Stephen D; Arnold, Hugh; Gavrilovi?, Jelena; Jaworski, Diane M; Yamamoto, Kazuhiro; Nagase, Hideaki; Seubert, Bastian; Krüger, Achim; Edwards, Dylan R 
Titel:
Metalloproteinase-dependent and -independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by a disintegrin and metalloproteinase with thrombospondin motifs-15. 
Abstract:
The ADAMTS proteinases are a family of secreted, matrix-associated enzymes that have diverse roles in the regulation of tissue organization and vascular homeostasis. Several of the 19 human family members have been identified as having either tumor promoting or suppressing roles. We previously demonstrated that decreased ADAMTS15 expression correlated with a worse clinical outcome in mammary carcinoma (e.g., Porter et al., Int J Cancer 2006; 118:1241-7). We have explored the effects of A Disinte...    »
 
Zeitschriftentitel:
Int J Cancer 
Jahr:
2015 
Band / Volume:
136 
Heft / Issue:
Seitenangaben Beitrag:
E14-26 
Sprache:
eng 
Print-ISSN:
0020-7136 
TUM Einrichtung:
Institut für experimentelle Onkologie und Therapieforschung