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Dokumenttyp:
journal article 
Autor(en):
Horsch, Marion; Aguilar-Pimentel, Juan Antonio; Bönisch, Clemens; Côme, Christophe; Kolster-Fog, Cathrine; Jensen, Klaus T; Lund, Anders H; Lee, Icksoo; Grossman, Lawrence I; Sinkler, Christopher; Hüttemann, Maik; Bohn, Erwin; Fuchs, Helmut; Ollert, Markus; Gailus-Durner, Valérie; de Angelis, Martin Hrab?; Beckers, Johannes 
Titel:
Cox4i2, Ifit2, and Prdm11 Mutant Mice: Effective Selection of Genes Predisposing to an Altered Airway Inflammatory Response from a Large Compendium of Mutant Mouse Lines. 
Abstract:
We established a selection strategy to identify new models for an altered airway inflammatory response from a large compendium of mutant mouse lines that were systemically phenotyped in the German Mouse Clinic (GMC). As selection criteria we included published gene functional data, as well as immunological and transcriptome data from GMC phenotyping screens under standard conditions. Applying these criteria we identified a few from several hundred mutant mouse lines and further characterized the...    »
 
Zeitschriftentitel:
PLoS ONE 
Jahr:
2015 
Band / Volume:
10 
Heft / Issue:
Seitenangaben Beitrag:
e0134503 
Sprache:
eng 
TUM Einrichtung:
Institut für Molekulare Allergologie und Umweltforschung; Klinik und Poliklinik für Dermatologie und Allergologie