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Dokumenttyp:
journal article 
Autor(en):
Spenlé, Caroline; Gasser, Isabelle; Saupe, Falk; Janssen, Klaus-Peter; Arnold, Christiane; Klein, Annick; van der Heyden, Michael; Mutterer, Jérome; Neuville-Méchine, Agnès; Chenard, Marie-Pierre; Guenot, Dominique; Esposito, Iréne; Slotta-Huspenina, Julia; Ambartsumian, Noona; Simon-Assmann, Patricia; Orend, Gertraud 
Titel:
Spatial organization of the tenascin-C microenvironment in experimental and human cancer. 
Abstract:
The extracellular matrix (ECM) molecule tenascin-C (TNC) promotes tumor progression. This has recently been demonstrated in the stochastic murine RIP1-Tag2 insulinoma model, engineered to either express TNC abundantly or to be devoid of TNC. However, our knowledge about organization of the TNC microenvironment is scant. Here we determined the spatial distribution of TNC together with other ECM molecules in murine RIP1-Tag2 insulinoma and human cancer tissue (insulinoma and colorectal carcinoma)....    »
 
Zeitschriftentitel:
Cell Adh Migr 
Jahr:
2015 
Band / Volume:
Heft / Issue:
1-2 
Seitenangaben Beitrag:
4-13 
Sprache:
eng 
Print-ISSN:
1933-6918 
TUM Einrichtung:
Chirurgiesche Klinik und Poliklinik; Institut für Allgemeine Pathologie und pathologische Anatomie