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Autor(en):
Wilkens, Jan J; Oelfke, Uwe 
Titel:
Fast multifield optimization of the biological effect in ion therapy 
Abstract:
In this paper, we present a new technique for simultaneous multifield optimization of the biological effect (i.e. relative biological effectiveness times dose) for intensity modulated radiotherapy with ion beams. It offers complete inverse treatment planning by taking into account planning constraints for the target volume as well as for organs at risk. The approach is based on the mixed irradiation formalism of the linear-quadratic model from radiobiology. We employ a novel objective function t...    »
 
Zeitschriftentitel:
Physics in Medicine and Biology 
Jahr:
2006 
Band / Volume:
51 
Heft / Issue:
12 
Seitenangaben Beitrag:
3127