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Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article 
Author(s):
Dekker, Tim J A; Balluff, Benjamin D; Jones, Emrys A; Schöne, Cédrik D; Schmitt, Manfred; Aubele, Michaela; Kroep, Judith R; Smit, Vincent T H B M; Tollenaar, Rob A E M; Mesker, Wilma E; Walch, Axel; McDonnell, Liam A 
Title:
Multicenter matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) identifies proteomic differences in breast-cancer-associated stroma. 
Abstract:
MALDI mass spectrometry imaging (MSI) has rapidly established itself as a powerful biomarker discovery tool. To date, no formal investigation has assessed the center-to-center comparability of MALDI MSI experiments, an essential step for it to develop into a new diagnostic method. To test such capabilities, we have performed a multicenter study focused on biomarkers of stromal activation in breast cancer. MALDI MSI experiments were performed in two centers using independent tissue banks, infrast...    »
 
Journal title abbreviation:
J Proteome Res 
Year:
2014 
Journal volume:
13 
Journal issue:
11 
Pages contribution:
4730-8 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
1535-3893 
TUM Institution:
Frauenklinik und Poliklinik