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Dokumenttyp:
journal article 
Autor(en):
Abd El Rahman, Mohamed Y; Rentzsch, Axel; Scherber, Philipp; Mebus, Siegrun; Miera, Oliver; Balling, Günther; Böttler, Petra; Dubowy, Karl-Otto; Farahwaschy, Birgit; Hager, Alfred; Kreuder, Joachim; Peters, Brigitte; Berger, Felix; Schulze-Neick, Ingram; Abdul-Khaliq, Hashim 
Titel:
Effect of bosentan therapy on ventricular and atrial function in adults with Eisenmenger syndrome. A prospective, multicenter study using conventional and Speckle tracking echocardiography. 
Abstract:
The effect of bosentan on the ventricular and atrial performance in patients with Eisenmenger syndrome is unclear. In adult patients with Eisenmenger syndrome, we aimed to evaluate the midterm effect of bosentan on physical exercise, ventricular and atrial function, and pulmonary hemodynamics.Forty adult patients before and after 24 weeks bosentan therapy underwent 6 min walk test, two-dimensional speckle tracking echocardiography, plasma NT-proBNP measurement and cardiac catheterization.After 2...    »
 
Zeitschriftentitel:
Clin Res Cardiol 
Jahr:
2014 
Band / Volume:
103 
Heft / Issue:
Seitenangaben Beitrag:
701-10 
Sprache:
eng 
Print-ISSN:
1861-0684 
TUM Einrichtung:
Klinik für Kinderkardiologie und angeborene Herzfehler