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Document type:
journal article 
Author(s):
Abd El Rahman, Mohamed Y; Rentzsch, Axel; Scherber, Philipp; Mebus, Siegrun; Miera, Oliver; Balling, Günther; Böttler, Petra; Dubowy, Karl-Otto; Farahwaschy, Birgit; Hager, Alfred; Kreuder, Joachim; Peters, Brigitte; Berger, Felix; Schulze-Neick, Ingram; Abdul-Khaliq, Hashim 
Title:
Effect of bosentan therapy on ventricular and atrial function in adults with Eisenmenger syndrome. A prospective, multicenter study using conventional and Speckle tracking echocardiography. 
Abstract:
The effect of bosentan on the ventricular and atrial performance in patients with Eisenmenger syndrome is unclear. In adult patients with Eisenmenger syndrome, we aimed to evaluate the midterm effect of bosentan on physical exercise, ventricular and atrial function, and pulmonary hemodynamics.Forty adult patients before and after 24 weeks bosentan therapy underwent 6 min walk test, two-dimensional speckle tracking echocardiography, plasma NT-proBNP measurement and cardiac catheterization.After 2...    »
 
Journal title abbreviation:
Clin Res Cardiol 
Year:
2014 
Journal volume:
103 
Journal issue:
Pages contribution:
701-10 
Language:
eng 
Print-ISSN:
1861-0684 
TUM Institution:
Klinik für Kinderkardiologie und angeborene Herzfehler