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Document type:
journal article 
Author(s):
Søgaard, Lise Vejby; Schilling, Franz; Janich, Martin A; Menzel, Marion I; Ardenkjaer-Larsen, Jan Henrik 
Title:
In vivo measurement of apparent diffusion coefficients of hyperpolarized ¹³C-labeled metabolites. 
Abstract:
The combination of hyperpolarized MRS with diffusion weighting (dw) allows for determination of the apparent diffusion coefficient (ADC), which is indicative of the intra- or extracellular localization of the metabolite. Here, a slice-selective pulsed-gradient spin echo sequence was implemented to acquire a series of dw spectra from rat muscle in vivo to determine the ADCs of multiple metabolites after a single injection of hyperpolarized [1- ¹³C]pyruvate. An optimal control optimized universal-...    »
 
Journal title abbreviation:
NMR Biomed 
Year:
2014 
Journal volume:
27 
Journal issue:
Pages contribution:
561-9 
Language:
eng 
Print-ISSN:
0952-3480 
TUM Institution:
Nuklearmedizinische Klinik und Poliklinik