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Document type:
journal article 
Author(s):
Max, Daniela; Kühnöl, Caspar D; Burdach, Stefan; Niu, Liguo; Staege, Martin S; Föll, Jürgen L 
Title:
Indoleamine-2,3-dioxygenase in an immunotherapy model for Ewing sarcoma. 
Abstract:
Interleukin-2 (IL2) transgenic Ewing sarcoma cells reduce tumor growth in vivo and in vitro. In the present study we analyzed the expression of immune suppressive indoleamine-2,3-dioxygenase (IDO) in this model.Expression of IDO was analyzed by polymerase chain reaction. The impact of the cluster of differentiation 137 (CD137)/CD137 ligand (CD137L) co-stimulatory system on expression of IDO and different cytokines was analyzed both in vivo and in vitro.Tumors that developed in vivo in the presen...    »
 
Journal title abbreviation:
Anticancer Res 
Year:
2014 
Journal volume:
34 
Journal issue:
11 
Pages contribution:
6431-41 
Language:
eng 
Print-ISSN:
0250-7005 
TUM Institution:
Kinderklinik und Poliklinik