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Dokumenttyp:
journal article 
Autor(en):
Lehmann, Frank M; Maurberger, Anna; Feicht, Samantha; Helm, Florian; Ladinig, Camilla; Kieback, Elisa; Uckert, Wolfgang; Kammertöns, Thomas; Kremmer, Elisabeth; Mautner, Josef; Gerbitz, Armin; Bornkamm, Georg W 
Titel:
Targeting high-grade B cell lymphoma with CD19-specific T cells. 
Abstract:
Adoptive T cell therapy is an important additional treatment option for malignant diseases resistant to chemotherapy. Using a murine high-grade B cell lymphoma model, we have addressed the question whether the B cell differentiation antigen CD19 can act as rejection antigen. CD19(-/-) mice inoculated with CD19(+) B cell lymphoma cells showed higher survival rates than WT mice and were protected against additional tumor challenge. T cell depletion prior to tumor transfer completely abolished the...    »
 
Zeitschriftentitel:
Int J Cancer 
Jahr:
2014 
Band / Volume:
135 
Heft / Issue:
Seitenangaben Beitrag:
1153-64 
Sprache:
eng 
Print-ISSN:
0020-7136 
TUM Einrichtung:
Kinderklinik und Poliklinik