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Dokumenttyp:
journal article 
Autor(en):
Sinnecker, Daniel; Laugwitz, Karl-Ludwig; Moretti, Alessandra 
Titel:
Induced pluripotent stem cell-derived cardiomyocytes for drug development and toxicity testing. 
Abstract:
Induced pluripotent stem cell (iPSC) technology is creating exciting new opportunities for cardiovascular research by providing platforms to study the mechanisms of disease pathogenesis that could lead to new therapies or reveal drug sensitivities. In this review, the potential usefulness of iPSC-derived cardiomyocytes in drug development as well as in drug toxicity testing is discussed, with a focus on the achievements that have been already made in this regard. Moreover, the crucial steps that...    »
 
Zeitschriftentitel:
Pharmacol Ther 
Jahr:
2014 
Band / Volume:
143 
Heft / Issue:
Seitenangaben Beitrag:
246-52 
Sprache:
eng 
Print-ISSN:
0163-7258 
TUM Einrichtung:
I. Medizinische Klinik und Poliklinik