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Dokumenttyp:
journal article 
Autor(en):
Postrach, Johannes; Schmidt, Maximilian; Thormann, Michael; Thein, Eckart; Burdorf, Lars; Reichart, Bruno; Sotlar, Karl; Walz, Christoph; Faber, Claudius; Bauer, Andreas; Schmoeckel, Michael; Kupatt, Christian; Hinkel, Rabea 
Titel:
Adeno-associated viral vector 2.9 thymosin ß4 application attenuates rejection after heart transplantation: results of a preclinical study in the pig. 
Abstract:
Graft survival is the most important factor for morbidity and mortality in cardiac transplantation. Improved immunosuppression significantly reduced early graft rejection. However, acute rejection may predispose to chronic rejection. Targeting both phases of the recipient's immune-reactivity by means of long-acting recombinant adeno-associated viral vectors (AAVs) encoding anti-inflammatory and cardioprotective factors appears to be a promising therapeutic approach. We investigate thymosin ß4 (T...    »
 
Zeitschriftentitel:
Transplantation 
Jahr:
2014 
Band / Volume:
98 
Heft / Issue:
Seitenangaben Beitrag:
835-43 
Sprache:
eng 
Print-ISSN:
0041-1337 
TUM Einrichtung:
I. Medizinische Klinik und Poliklinik