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Dokumenttyp:
journal article 
Autor(en):
Stoelben, Susanne; Arns, Wolfgang; Renders, Lutz; Hummel, Jürgen; Mühlfeld, Anja; Stangl, Manfred; Fischereder, Michael; Gwinner, Wilfried; Suwelack, Barbara; Witzke, Oliver; Dürr, Michael; Beelen, Dietrich W; Michel, Detlef; Lischka, Peter; Zimmermann, Holger; Rübsamen-Schaeff, Helga; Budde, Klemens 
Titel:
Preemptive treatment of Cytomegalovirus infection in kidney transplant recipients with letermovir: results of a Phase 2a study. 
Abstract:
Cytomegalovirus (CMV) infection remains a significant cause of morbidity and mortality in transplant recipients. Letermovir (AIC246), is a novel anti-HCMV drug in development, acting via a novel mechanism of action. In this proof-of-concept trial with first administration of letermovir to patients, 27 transplant recipients with active CMV replication were randomly assigned to a 14-day oral treatment regimen of either letermovir 40 mg twice a day, letermovir 80 mg once a day, or local standard of...    »
 
Zeitschriftentitel:
Transpl Int 
Jahr:
2014 
Band / Volume:
27 
Heft / Issue:
Seitenangaben Beitrag:
77-86 
Sprache:
eng 
Print-ISSN:
0934-0874 
TUM Einrichtung:
Abteilung für Nephrologie