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Document type:
journal article 
Author(s):
Straubinger, Kathrin; Paul, Sabine; Prazeres da Costa, Olivia; Ritter, Manuel; Buch, Thorsten; Busch, Dirk H; Layland, Laura E; Prazeres da Costa, Clarissa U 
Title:
Maternal immune response to helminth infection during pregnancy determines offspring susceptibility to allergic airway inflammation. 
Abstract:
Schistosomiasis, a chronic helminth infection, elicits distinct immune responses within the host, ranging from an initial TH1 and subsequent TH2 phase to a regulatory state, and is associated with dampened allergic reactions within the host.We sought to evaluate whether non-transplacental helminth infection during pregnancy alters the offspring's susceptibility to allergy.Ovalbumin-induced allergic airway inflammation was analyzed in offspring from Schistosoma mansoni-infected mothers mated duri...    »
 
Journal title abbreviation:
J Allergy Clin Immunol 
Year:
2014 
Journal volume:
134 
Journal issue:
Pages contribution:
1271-1279.e10 
Language:
eng 
Print-ISSN:
0091-6749 
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene