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Document type:
journal article 
Author(s):
Käbisch, Romy; Mejías-Luque, Raquel; Gerhard, Markus; Prinz, Christian 
Title:
Involvement of Toll-like receptors on Helicobacter pylori-induced immunity. 
Abstract:
Dendritic cells (DCs) play a major role in the innate immune response since they recognize a broad repertoire of PAMPs mainly via Toll-like receptors (TLRs). During Helicobacter pylori (H. pylori) infection, TLRs have been shown to be important to control cytokine response particularly in murine DCs. In the present study we analyzed the effect of blocking TLRs on human DCs. Co-incubation of human DCs with H. pylori resulted in the release of the pro-inflammatory cytokines IL-12p70, IL-6 and IL-1...    »
 
Journal title abbreviation:
PLoS ONE 
Year:
2014 
Journal volume:
Journal issue:
Pages contribution:
e104804 
Language:
eng 
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene