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Dokumenttyp:
journal article 
Autor(en):
Käbisch, Romy; Mejías-Luque, Raquel; Gerhard, Markus; Prinz, Christian 
Titel:
Involvement of Toll-like receptors on Helicobacter pylori-induced immunity. 
Abstract:
Dendritic cells (DCs) play a major role in the innate immune response since they recognize a broad repertoire of PAMPs mainly via Toll-like receptors (TLRs). During Helicobacter pylori (H. pylori) infection, TLRs have been shown to be important to control cytokine response particularly in murine DCs. In the present study we analyzed the effect of blocking TLRs on human DCs. Co-incubation of human DCs with H. pylori resulted in the release of the pro-inflammatory cytokines IL-12p70, IL-6 and IL-1...    »
 
Zeitschriftentitel:
PLoS ONE 
Jahr:
2014 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
e104804 
Sprache:
eng 
TUM Einrichtung:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene