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Document type:
journal article 
Author(s):
Sollinger, Daniel; Eißler, Ruth; Lorenz, Steffen; Strand, Susanne; Chmielewski, Stefan; Aoqui, Cristiane; Schmaderer, Christoph; Bluyssen, Hans; Zicha, Josef; Witzke, Oliver; Scherer, Elias; Lutz, Jens; Heemann, Uwe; Baumann, Marcus 
Title:
Damage-associated molecular pattern activated Toll-like receptor 4 signalling modulates blood pressure in L-NAME-induced hypertension. 
Abstract:
Recent publications have shed new light on the role of the adaptive and innate immune system in the pathogenesis of hypertension. However, there are limited data whether receptors of the innate immune system may influence blood pressure. Toll-like receptor 4 (TLR4), a pattern recognition receptor, is a key component of the innate immune system, which is activated by exogenous and endogenous ligands. Hypertension is associated with end-organ damage and thus might lead to the release of damage-ass...    »
 
Journal title abbreviation:
Cardiovasc Res 
Year:
2014 
Journal volume:
101 
Journal issue:
Pages contribution:
464-72 
Language:
eng 
Print-ISSN:
0008-6363 
TUM Institution:
Abteilung für Nephrologie; Hals-, Nasen-, Ohrenklinik und Poliklinik