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Dokumenttyp:
journal article 
Autor(en):
Flaquer, Antònia; Baumbach, Clemens; Kriebel, Jennifer; Meitinger, Thomas; Peters, Annette; Waldenberger, Melanie; Grallert, Harald; Strauch, Konstantin 
Titel:
Mitochondrial genetic variants identified to be associated with BMI in adults. 
Abstract:
It has been suggested that mitochondrial dysfunction plays a role in metabolic disorders including obesity, diabetes, and hypertension. The fact that mitochondrial defects can be accumulated over time as a normal part of aging may explain why some individuals can eat all sorts of foods and remain at normal weight while they are young. However, around the fourth decade of life there is a trend towards "middle-age spread" with weight gain and the body's decreasing ability to metabolize calories ef...    »
 
Zeitschriftentitel:
PLoS ONE 
Jahr:
2014 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
e105116 
Sprache:
eng 
TUM Einrichtung:
Institut für Humangenetik