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Dokumenttyp:
journal article 
Autor(en):
Meder, Benjamin; Rühle, Frank; Weis, Tanja; Homuth, Georg; Keller, Andreas; Franke, Jennifer; Peil, Barbara; Lorenzo Bermejo, Justo; Frese, Karen; Huge, Andreas; Witten, Anika; Vogel, Britta; Haas, Jan; Völker, Uwe; Ernst, Florian; Teumer, Alexander; Ehlermann, Philipp; Zugck, Christian; Friedrichs, Frauke; Kroemer, Heyo; Dörr, Marcus; Hoffmann, Wolfgang; Maisch, Bernhard; Pankuweit, Sabine; Ruppert, Volker; Scheffold, Thomas; Kühl, Uwe; Schultheiss, Hans-Peter; Kreutz, Reinhold; Ertl, Georg; An...    »
 
Titel:
A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy. 
Abstract:
Dilated cardiomyopathy (DCM) is one of the leading causes for cardiac transplantations and accounts for up to one-third of all heart failure cases. Since extrinsic and monogenic causes explain only a fraction of all cases, common genetic variants are suspected to contribute to the pathogenesis of DCM, its age of onset, and clinical progression. By a large-scale case-control genome-wide association study we aimed here to identify novel genetic risk loci for DCM.Applying a three-staged study desig...    »
 
Zeitschriftentitel:
Eur Heart J 
Jahr:
2014 
Band / Volume:
35 
Heft / Issue:
16 
Seitenangaben Beitrag:
1069-77 
Sprache:
eng 
Print-ISSN:
0195-668X 
TUM Einrichtung:
Institut für Humangenetik