Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Fichna, J; Sa?aga, M; Stuart, J; Saur, D; Sobczak, M; Zatorski, H; Timmermans, J-P; Bradshaw, H B; Ahn, K; Storr, M A 
Titel:
Selective inhibition of FAAH produces antidiarrheal and antinociceptive effect mediated by endocannabinoids and cannabinoid-like fatty acid amides. 
Abstract:
The endogenous cannabinoid system (ECS) plays a crucial role in multiple physiological processes in the central nervous system and in the periphery. The discovery that selective cannabinoid (CB) receptor agonists exert a potent inhibitory action on gastrointestinal (GI) motility and pain has placed the ECS in the center of attention as a possible target for the treatment of functional GI diseases. However, side effects of CB agonists prompted the search for novel therapeutic targets. Here, the e...    »
 
Zeitschriftentitel:
Neurogastroenterol Motil 
Jahr:
2014 
Band / Volume:
26 
Heft / Issue:
Seitenangaben Beitrag:
470-81 
Sprache:
eng 
Print-ISSN:
1350-1925 
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik