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Document type:
journal article 
Author(s):
Wagener, Jeanette; Malireddi, R K Subbarao; Lenardon, Megan D; Köberle, Martin; Vautier, Simon; MacCallum, Donna M; Biedermann, Tilo; Schaller, Martin; Netea, Mihai G; Kanneganti, Thirumala-Devi; Brown, Gordon D; Brown, Alistair J P; Gow, Neil A R 
Title:
Fungal chitin dampens inflammation through IL-10 induction mediated by NOD2 and TLR9 activation. 
Abstract:
Chitin is an essential structural polysaccharide of fungal pathogens and parasites, but its role in human immune responses remains largely unknown. It is the second most abundant polysaccharide in nature after cellulose and its derivatives today are widely used for medical and industrial purposes. We analysed the immunological properties of purified chitin particles derived from the opportunistic human fungal pathogen Candida albicans, which led to the selective secretion of the anti-inflammator...    »
 
Journal title abbreviation:
PLoS Pathog 
Year:
2014 
Journal volume:
10 
Journal issue:
Pages contribution:
e1004050 
Language:
eng 
Print-ISSN:
1553-7366 
TUM Institution:
Klinik und Poliklinik für Dermatologie und Allergologie