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Document type:
journal article 
Author(s):
Sinnecker, Daniel; Laugwitz, Karl-Ludwig; Moretti, Alessandra 
Title:
Induced pluripotent stem cell-derived cardiomyocytes for drug development and toxicity testing. 
Abstract:
Induced pluripotent stem cell (iPSC) technology is creating exciting new opportunities for cardiovascular research by providing platforms to study the mechanisms of disease pathogenesis that could lead to new therapies or reveal drug sensitivities. In this review, the potential usefulness of iPSC-derived cardiomyocytes in drug development as well as in drug toxicity testing is discussed, with a focus on the achievements that have been already made in this regard. Moreover, the crucial steps that...    »
 
Journal title abbreviation:
Pharmacol Ther 
Year:
2014 
Journal volume:
143 
Journal issue:
Pages contribution:
246-52 
Language:
eng 
Print-ISSN:
0163-7258 
TUM Institution:
I. Medizinische Klinik und Poliklinik