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Dokumenttyp:
journal article 
Autor(en):
Dongmo, Alain Bertrand; Nkeng-Efouet, Pepin Alango; Devkota, Krishna Prasad; Wegener, Jörg W; Sewald, Norbert; Wagner, Hildebert; Vierling, Wolfgang 
Titel:
Tetra-acetylajugasterone a new constituent of Vitex cienkowskii with vasorelaxant activity. 
Abstract:
Tetra-acetylajugasterone C (TAAC) was found to be one of the naturally occurring compounds of the Cameroonian medicinal plant Vitex cienkowskii which is responsible for a vasorelaxant activity of an extract of this plant. The evaluation of the underlying mechanisms for the relaxing effect of TAAC was determined using aortic rings of rats and mice. TAAC produced a concentration-dependent relaxation in rat artery rings pre-contracted with 1?M noradrenaline (IC50: 8.40?M) or 60mM KCl (IC50: 36.30?M...    »
 
Zeitschriftentitel:
Phytomedicine 
Jahr:
2014 
Band / Volume:
21 
Heft / Issue:
Seitenangaben Beitrag:
787-92 
Sprache:
eng 
Print-ISSN:
0944-7113 
TUM Einrichtung:
Institut für Pharmakologie und Toxikologie