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Dokumenttyp:
journal article 
Autor(en):
Ahles, Andrea; Engelhardt, Stefan 
Titel:
Polymorphic variants of adrenoceptors: pharmacology, physiology, and role in disease. 
Abstract:
The human genome encodes nine different adrenoceptor genes. These are grouped into three families, namely, the ?1-, ?2-, and ?-adrenoceptors, with three family members each. Adrenoceptors are expressed by most cell types of the human body and are primary targets of the catecholamines epinephrine and norepinephrine that are released from the sympathetic nervous system during its activation. Upon catecholamine binding, adrenoceptors change conformation, couple to and activate G proteins, and there...    »
 
Zeitschriftentitel:
Pharmacol Rev 
Jahr:
2014 
Band / Volume:
66 
Heft / Issue:
Seitenangaben Beitrag:
598-637 
Sprache:
eng 
Print-ISSN:
0031-6997 
TUM Einrichtung:
Institut für Pharmakologie und Toxikologie