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Dokumenttyp:
journal article 
Autor(en):
Schmutz, Isabelle; Chavan, Rohit; Ripperger, Jürgen A; Maywood, Elizabeth S; Langwieser, Nicole; Jurik, Angela; Stauffer, Anja; Delorme, James E; Moosmang, Sven; Hastings, Michael H; Hofmann, Franz; Albrecht, Urs 
Titel:
A specific role for the REV-ERB?-controlled L-Type Voltage-Gated Calcium Channel CaV1.2 in resetting the circadian clock in the late night. 
Abstract:
Within the suprachiasmatic nucleus (SCN) of the hypothalamus, circadian timekeeping and resetting have been shown to be largely dependent on both membrane depolarization and intracellular second-messenger signaling. In both of these processes, voltage-gated calcium channels (VGCCs) mediate voltage-dependent calcium influx, which propagates neural impulses by stimulating vesicle fusion and instigates intracellular pathways resulting in clock gene expression. Through the cumulative actions of thes...    »
 
Zeitschriftentitel:
J Biol Rhythms 
Jahr:
2014 
Band / Volume:
29 
Heft / Issue:
Seitenangaben Beitrag:
288-98 
Sprache:
eng 
Print-ISSN:
0748-7304 
TUM Einrichtung:
Institut für Pharmakologie und Toxikologie