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Document type:
journal article 
Author(s):
Schmutz, Isabelle; Chavan, Rohit; Ripperger, Jürgen A; Maywood, Elizabeth S; Langwieser, Nicole; Jurik, Angela; Stauffer, Anja; Delorme, James E; Moosmang, Sven; Hastings, Michael H; Hofmann, Franz; Albrecht, Urs 
Title:
A specific role for the REV-ERB?-controlled L-Type Voltage-Gated Calcium Channel CaV1.2 in resetting the circadian clock in the late night. 
Abstract:
Within the suprachiasmatic nucleus (SCN) of the hypothalamus, circadian timekeeping and resetting have been shown to be largely dependent on both membrane depolarization and intracellular second-messenger signaling. In both of these processes, voltage-gated calcium channels (VGCCs) mediate voltage-dependent calcium influx, which propagates neural impulses by stimulating vesicle fusion and instigates intracellular pathways resulting in clock gene expression. Through the cumulative actions of thes...    »
 
Journal title abbreviation:
J Biol Rhythms 
Year:
2014 
Journal volume:
29 
Journal issue:
Pages contribution:
288-98 
Language:
eng 
Print-ISSN:
0748-7304 
TUM Institution:
Institut für Pharmakologie und Toxikologie